Nadezhda Korostyleva

Nadezhda Korostyleva

I build medical devices at the millimetre and micrometre scale — phototherapy patches you wear on a wound, microfluidic chambers that keep brain tissue alive, and the electronics that drive them.

M.S. Biomedical Engineering, University of South Florida
Graduate Research Engineer, Acousto-Bioelectronics Lab
Tampa, Florida

LED source Microlens Microneedle Wound bed 500 µm
Working principle of the MAP wound patch, in cross-section: LED sources at the top, microlenses beneath them, and microneedles carrying antimicrobial blue light past the skin surface into the wound bed. Schematic, not to scale.

Selected work

MAP — microneedle phototherapy wound patch

Acousto-Bioelectronics Lab, USF — 2025 to present

A wearable MEMS patch that delivers antimicrobial blue light below the skin surface. I led it end to end, from device design and fabrication through in vitro results and in vivo validation. Redesigning the drive electronics and optics cut peak device temperature by 30 °C and power draw by two orders of magnitude.

MicrofabricationOpticsThermal designFirst-author IEEE MEMS paper

Microfluidic perfusion chamber for brain slices

Acousto-Bioelectronics Lab with a collaborating neuroscience lab, USF — 2025 to present

Brain slices die within hours, which caps how long an optogenetics experiment can run. I am building a perfusion chamber to extend viability by roughly 30×, and cut the device build time from two days to two hours along the way.

MicrofluidicsCNC machiningCleanroom fabricationOptogenetics

Semi-automated blood pressure regulation for ICU patients

Senior design with MiracleBots, LLC — 2024 to 2025

A closed-loop system pairing a non-invasive cuff with a peristaltic pump for nicardipine delivery, designed against ISO 14971, 13485, 81060-2 and IEC 60601-2-24. Three of us built every part of it: hardware, CAD, signal processing, the patient-response model, and the clinician app.

Regulated designClosed-loop controlHuman subject testingPython / C++ / MATLAB

Wireless EOG driver drowsiness monitor

Junior design, USF — 2024

A wearable that reads eye movement to track blink frequency, a validated marker of sleepiness, and streams it over BLE to a companion phone app. Selected as one of the top three teams of fifteen at the 2024 Florida Medical Manufacturing Consortium.

Biopotential sensingBLEMobile app

Hardware workshops — IEEE Computer Society at USF

Hardware Tech Lead — 2025 to present

I design and teach the chapter's hardware curriculum: two embedded builds so far, an optical Morse-code link that uses a reverse-biased LED as a photodetector, and a two-way Wi-Fi audio system over I²S. Over 200 attendees and 100+ devices built.

Embedded systemsParticle ArgonESP32 / I²SCurriculum

Publications

What I work with

Fabrication

Cleanroom processing and photolithography, mask design in L-Edit, microneedle and microlens array fabrication, CNC machining, FDM and SLA 3D printing.

Design and simulation

SOLIDWORKS, Autodesk Fusion, COMSOL Multiphysics for thermal and optical modelling.

Electronics and firmware

Embedded development on ESP32 and Particle Argon, I²S and analog sensor interfacing, BLE and Wi-Fi links, breadboard prototyping and hardware debug.

Software and analysis

Python, C++, MATLAB, SPSS, machine learning for physiological response modelling.

Wet lab

In vitro work with mammalian and human cell lines; in vivo rodent studies including surgery and imaging, IACUC certified.

Standards

ISO 14971 risk management, ISO 13485 quality systems, ISO 81060-2, IEC 60601-2-24.

Awards and programs